Subject(s)
Adult , Ascariasis/therapy , Biliary Tract Diseases/therapy , Combined Modality Therapy , Endoscopy , Female , HumansABSTRACT
Endoscopic clips have been used mainly for control of gastrointestinal (GI) bleeding and occasionally for closure of GI perforations. However, closure of spontaneous esophageal perforation (Boerhaave's syndrome) by clipping has not been reported. We described successful non-surgical closure of spontaneous esophageal perforation by endoscopic clipping in a patient with bilateral pyopneumothorax and septicemia.
Subject(s)
Diagnosis, Differential , Esophageal Perforation/diagnosis , Esophagoscopy , Humans , Male , Middle Aged , Rupture, SpontaneousABSTRACT
Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.